Neeltje van Haren

Van Haren foto

Dr. Neeltje van Haren

  • psychoses
  • genetic risks
  • environmental risks
  • structure and connections
telefoon
+31 88 75 57130
email
N.E.M.vanHaren@umcutrecht.nl

Biography

Neeltje van Haren obtained her PhD in Utrecht in 2004 with Prof. Rene S. Kahn. She remained at the Department of Psychiatry as an assistant professor in psychiatric neuroimaging. In 2012, she became associate professor at the same department.

Her research focuses on the underlying neurobiological and cognitive mechanisms of psychiatric illnesses, in particular schizophrenia and bipolar disorder. Neeltje has performed a large longitudinal magnetic resonance imaging (MRI) study in patients with schizophrenia showing excessive brain tissue loss during the course of the illness. She has been studying confounding factors, such as antipsychotic medication use, illness outcome, cannabis and nicotine intake on these progressive brain changes. Moreover, she aims to unravel the genetic and environmental contribution to abnormal brain volume (change) in schizophrenia and bipolar twin and family samples. This is not only a local effort, using family data acquired at the department, but also involves close collaboration with the Institute of Psychiatry, Psychology, and Neuroscience (IOPNN, London, UK) and Neeltje is an active participant in the ENIGMA consortium.

More recently she extended her work to include cognitive social neuroscience in general and self-referential processes in health and disease in particular. Her aim is to use existing cognitive paradigms from social psychology (e.g., self-agency, joint action, social distance, bodily illusions) to understand psychotic symptoms and poor social functioning in patients with schizophrenia and in offspring of patients with schizophrenia and bipolar disorder. The focus will be on self-processes, self-other integration, and theory of mind. For this purpose, studies in healthy populations are equally important as studies in diseased populations. By using fMRI and sMRI the brain areas involved in self-processes, theory of mind and self-other integration will be elucidated.

Research line and group

Research line
Neurobiological and cognitive basis of schizophrenia and bipolar disorder
Number of PhD students
N=7
Number of postdocs
N=2

Personal fellowships and awards

  • NWO-VIDI and ASPASIA grant " Did I do that? The experience of self-agency in health and schizophrenia. " 2012
  • ‘Stimulerings’ Associate Professor from the UMCU, 2012
  • Focus & Massa grant, Neuroscience and Cognition Utrecht (UU): “Structural and functional neural correlates of the experience of self-agency in health and schizophrenia”. 2009
  • ZonMW TOP Grants (co-applicant), 2008 and 2012
  • Young Investigator Travel Award - International Congress on Schizophrenia Research, 2007

Most recent key publications

  • Van Haren NEM, Cahn W, Hulshoff Pol HE, Kahn RS. 2013. Confounders of excessive brain volume loss in schizophrenia. Neuroscience & Biobehavioral Reviews, 37, 10, 2418-2423.
  • Renes RA, van Haren NEM, Aarts H, Vink M. 2014. An exploratory fMRI study into inferences of self-agency. Social cognitive and affective neuroscience, 10 (5), 708-712,2015
  • Renes RA, van der Weiden A, Prikken M, Kahn RS, Aarts H, van Haren NEM. 2015. Abnormalities in the experience of self-agency in schizophrenia: A replication study. Schizophrenia research, 164 (1), 210-213
  • Kubota M, van Haren NEM, Haijma SV, Schnack HG, Cahn W, Hulshoff Pol HE, Kahn, RS. 2015. Association of IQ changes and progressive brain changes in patients with schizophrenia. JAMA psychiatry, 72 (8), 803-812
  • van der Weiden A, Prikken M, van Haren NEM. In Press 2015. Self-Other Integration and Distinction in Schizophrenia: A Theoretical Analysis and a Review of the Evidence. Neuroscience & Biobehavioral Reviews