René Mandl


Dr. René Mandl

  • psychoses
+31 88 7559705
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René Mandl obtained his Masters degree in Informatics at the University of Amsterdam in 1996 after which he started to work as a scientific programmer at the Department of Psychiatry of the University Medical Center Utrecht. He started his PhD project (part-time) in 2004 and in 2009 he successfully defended his PhD thesis titled: “Tract-based analysis in schizophrenia: Measuring structure and function along white matter tracts”. Currently he works as an assistant professor in the group of Proffesor Hulshoff Pol and his research expertise includes diffusion weighted imaging, structural MRI, functional MRI, MR spectroscopy and the development of new analysis methods. He is involved in several international collaborations such as ENIGMA, TACTICS and the EU-AIMS project.



Research line and group

Research line
New analysis methods for (ultra-) high field MRI.
Number of PhD students
Number of postdocs

Most recent key publications

  • Marsman A, Mandl RC, van den Heuvel MP, Boer VO, Wijnen JP, Klomp DW, Luijten PR, Hilleke E HP, Glutamate changes in healthy young adulthood, Eur Neuropsychopharmacol. 2012 Dec 12, doi:pii: S0924-977X(12)00315-X.
  • Mandl RC, Rais M, van Baal GC, van Haren NE, Cahn W, Kahn RS, Hulshoff Pol HE., Altered white matter connectivity in never-medicated patients with schizophrenia, Hum Brain Mapp. 2012 Mar 28. doi: 10.1002/hbm.22075.
  • Mandl RC, van den Heuvel MP, Klomp DW, Boer VO, Siero JC, Luijten PR, Hulshoff Pol HE, Tract-based magnetic resonance spectroscopy of the cingulum bundles at 7 T, Hum Brain Mapp. 2012 Jul;33(7):1503-11. doi: 10.1002/hbm.21302
  • Mandl RC, Schnack HG, Luigjes J, van den Heuvel MP, Cahn W, Kahn RS, Hulshoff Pol HE, Tract-based analysis of magnetization transfer ratio and diffusion tensor imaging of the frontal and frontotemporal connections in schizophrenia, Schizophr Bull. 2010 Jul;36(4):778-87. doi: 10.1093/schbul/sbn161.
  • Mandl RC, Schnack HG, Zwiers MP, van der Schaaf A, Kahn RS, Hulshoff Pol HE, Functional diffusion tensor imaging: measuring task-related fractional anisotropy changes in the human brain along white matter tracts, PLoS One. 2008;3(11):e3631. doi: 10.1371/j