Patrick de Zeeuw

De Zeeuw foto

Dr. Patrick de Zeeuw

  • developmental disorders
  • structure and connections
  • from research to care
+31 88 75 53227
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Patrick de Zeeuw is a post-doctoral researcher at the NICHE Neuroimaging Lab, and a psychologist in clinical training towards the Dutch healthcare psychologist (GZ-psycholoog) registration, both at the Developmental Disorders Unit within the Department of Psychiatry. He completed his MSc in Clinical Neuropsychology (specialisation: Child Neuropsychology) at VU University Amsterdam in 2005. Afterwards, he worked as a teaching/research assistant with the departments of Clinical Neuropsychology at both VU University Amsterdam and Leiden University. He joined the NICHE lab in October 2006 as a PhD student where he investigated brain development and neuropsychological factors in childhood ADHD using a combination of MRI, cognitive, genetic and questionnaire approaches. In October 2011, he received his PhD with a dissertation entitled Neurobiological Heterogeneity in ADHD.

The main research interests of dr. De Zeeuw are the neurobiological and neuropsychological background of developmental disorders. He has been involved in a broad spectrum of clinical and basic research into ADHD since 2003. The main focus of his current research within the lab of prof.dr. Sarah Durston, continues to be on brain development in ADHD. In addition, together with PhD students in the lab, he works on the hypothesis that deviations in separable brain networks that are crucial to cognitive control, temporal processing and sensitivity to reward, may independently be associated with ADHD. He is also a strong advocate of integration of basic research into clinical practice and of combining both clinical and research activities to a broader and fuller understanding of developmental disorders. 

Research line and group

Research line
Developmental Disorders (ADHD)
Number of PhD students

Personal fellowships and awards

  • Recipient of the annual MSc Thesis Prize from the Netherlands Society for Neuropsychology (thesis: Predictors of Dimensional and Clinical Response to Methylphenidate in Children with ADHD, 2006)
  • Travel grant for John Merck Summerschool on The Biology of Developmental Disabilities. (2007).

Most recent key publications

  • De Zeeuw, P., Van Belle, J., Van Dijk, S., Weusten, J., Koeleman, B., Janson, E., Van Engeland, H., & Durston, S. (2013). Imaging gene and environmental effects on cerebellum in Attention-Deficit/Hyperactivity Disorder and typical development. NeuroImage: Clinical, 2, 103–110
  • De Zeeuw, P., Weusten, J., Van Dijk, S., Van Belle, J., & Durston, S. (2012). Deficits in cognitive control, timing and reward sensitivity appear to be dissociable in ADHD. PLoS One, 7(12), e51416.
  • De Zeeuw, P., Schnack H.G., Van Belle, J.,Weusten, J., Van Dijk, S., Langen, M., Brouwer, R.M., Van Engeland, H., & Durston, S. (2012). Differential brain development with low and high IQ in Attention-Deficit/Hyperactivity Disorder. PLoS One, 7(4), e35770
  • Schweren, L.J.S., De Zeeuw, P., & Durston, S. (in press, epub ahead of print). MR Imaging of the effects of methylphenidate on brain structure and function in Attention-Deficit/Hyperactivity Disorder. European Neuropsychopharmacology. DOI: 10.1016/j.euron
  • De Zeeuw, P., Mandl, R.C.W., Hulshoff-Pol, H.E., Van Engeland, H., & Durston, S. (2012). Decreased frontostriatal microstructural organization in ADHD. Human Brain Mapping. 33: 1941–1951.