Mervyn Vergouwen

Vergouwen

Dr. Mervyn Vergouwen

  • stroke
  • translational research
telefoon
+31 88 7550455
email
m.d.i.vergouwen@umcutrecht.nl

Biography

Mervyn Vergouwen obtained his PhD degree at the University of Amsterdam / Academic Medical Center in 2009. The title of his PhD was ‘Delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage – the role of coagulation and fibrinolysis’. From 2009-2010 he did a clinical/research stroke fellowship at the University of Toronto, Canada. After his return to the Netherlands, he worked as a postdoc at the Laboratory of Experimental Vascular Medicine at the Academic Medical Center to study the role of microthrombosis in the pathogenesis of delayed cerebral ischemia after subarachnoid hemorrhage in a mouse model. In 2011 he accepted a position as a staff neurologist at the UMC Utrecht and joined Prof. Gabriel Rinkel’s research group on aneurysmal subarachnoid hemorrhage.

His research focuses on unruptured intracranial aneurysms, diagnosis of (aneurysmal) subarachnoid hemorrhage, and brain injury after subarachnoid hemorrhage.  This includes all processes that occur in the (sub)acute setting, including the initial hemorrhage and subsequent in-hospital complications (such as rebleeding, delayed cerebral ischemia, hydrocephalus, and infections), and the relationship of these processes with micro- and macrostructural brain injury , disability and cognitive impairment.

His work was published in >70 publications and to date (September 2015) has been cited >1600 times.

Mervyn Vergouwen is an International Scientific Committee member of the International Conference on Neurovascular Events after Subarachnoid Hemorrhage.

Research line and group

Research line
Subarachnoid hemorrhage
Number of PhD students
N=4

Personal fellowships and awards

  • Netherlands Heart Foundation Dr. E. Dekker postdoc personal grant (2011)
  • Niels Stensen award for stroke fellowship in Toronto, Canada (2009)
  • Jacob Jongbloed Talent Society (2014)

Most recent key publications

  • Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, Hänggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society’s Multidisciplinary Consensus Conference. Neurocrit Care 2011;15:211-240.
  • Vergouwen MD, Vermeulen M, van Gijn J, Rinkel GJ, Wijdicks EF, Muizelaar JP, Mendelow AD, Juvela S, Yonas H, Terbrugge KG, Macdonald RL, Diringer MN, Broderick JP, Dreier JP, Roos YB. Definition of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage as an outcome event in clinical trials and observational studies - Proposal of a multidisciplinary research group. Stroke 2010;41:2391-2395.
  • Vergouwen MD, Meijers JC, Geskus RB, Coert BA, Horn J, Stroes ES, van der Poll T, Vermeulen M, Roos YB. Biologic effects of simvastatin in patients with aneurysmal subarachnoid hemorrhage - a double-blind, placebo-controlled randomized trial. J Cereb Blood Flow Metab 2009;29:1444-1453.
  • Vergouwen MD, Vermeulen M, Coert BA, Stroes ES, Roos YB. Microthrombosis after aneurysmal subarachnoid hemorrhage - an additional explanation for delayed cerebral ischemia. J Cereb Blood Flow Metab 2008;28:1761-1770.
  • Vergouwen MD, Vermeulen M, Roos YB. Effect of nimodipine on outcome in patients with traumatic subarachnoid haemorrhage - a systematic review. Lancet Neurol 2006;5:1029-1032.