Hugo Schnack

Schnack foto

Dr. Hugo Schnack

  • developmental disorders
  • psychoses
  • structure and connections
+31 88 75 58459
Ga naar LinkedIn profiel


After studying experimental and theoretical physics at the Free University Amsterdam (1987-1991), Hugo Schnack carried out a PhD research in the Physics of condensed matter group at the same university. On September 1st, 1995, he defended his thesis: “Activation energies from magnetization relaxation & vice versa in high-Tc superconductors”.

 From September 1995 he worked as a post-doc in the Neuroimaging section of the Department of psychiatry of the University Medical Center Utrecht, and from 1998 onwards as an assistant professor.

 During the first years, he developed the image processing and analyis system of the group. As of 2015, thousands of scans have been analyzed using this pipeline. Gradually his research interests moved from image analysis of structural MRI brain scans to (longitudinal) brain data analysis and modeling, and from group-level statistics to individual predictions using Machine Learning. His research involves the study of both healhty development and psychiatric disorders including schizophrenia and bipolar disorder. His work has been published in more than 200 publications which have been cited more than 5000 times (2015).

Research line and group

Research line
Brain image classification
Number of PhD students
Number of postdocs

Personal fellowships and awards

  • Seed money Dynamics of Youth, University Utrecht, 2013 (PODIUM project)

Most recent key publications

  • Schnack HG, van Haren NE, Brouwer RM, Evans A, Durston S, Boomsma DI, Kahn RS, Hulshoff Pol HE, Changes in thickness and surface area of the human cortex and their relationship with intelligence. Cereb Cortex 25:1608-1617 (2015).
  • Schnack HG, Nieuwenhuis M, van Haren NE, Abramovic L, Scheewe TW, Brouwer RM, Hulshoff Pol HE, Kahn RS, Can structural MRI aid in clinical classification? A machine learning study in two independent samples of patients with schizophrenia, bipolar disorder and healthy subjects. Neuroimage 84:299-306 (2014)
  • Mandl RC, Schnack HG, Zwiers MP, Kahn RS, Hulshoff Pol HE, Functional diffusion tensor imaging at 3 Tesla. Front Hum Neurosci 7:817 (2013).
  • Nieuwenhuis M, van Haren NE, Hulshoff Pol HE, Cahn W, Kahn RS, Schnack HG, Classification of schizophrenia patients and healthy controls from structural MRI scans in two large independent samples. NeuroImage 61:606-612 (2012).
  • Brouwer RM, Hulshoff Pol HE, Schnack HG, Segmentation of MRI Brain Scans Using Non-Uniform Partial Volume Densities. NeuroImage 49:467-477 (2010).