Gabriël Rinkel

Profiel G Rinkel

Prof. Gabriël Rinkel

  • stroke
+31 88 7558600


Gabriel Rinkel (1961) studied medicine in Utrecht. During medical study he did 6 months research at the Rudolf Magnus Institute for pharmacology in Utrecht on the effect of neuropeptides on behaviour. Later during medical study he did research at the Addiction Research Foundation, University of Toronto, Canada. After graduating in 1987 he started his residency in neurology and in the meantime research for his thesis on perimesencephalic subarachnoid haemorrhage; both were completed in 1991. For his thesis he received in 1992 the Synthélabo Research Award from the ‘Société de Ciculation et Métabolism du Cerveau’ at the CHU Lariboisière-Saint Louis in Paris. In 1997 he received the award “Teacher of the year” of the Faculty of medicine, and in 1998 the Stroke Research Award at the annual European Stroke Conference in Edinburgh. From 1999 to 2004 he was Clinical Established Investigator of the Netherlands Heart foundation. In 2002 he was appointed as Professor of Neurology. From 2003 through 2009 he chaired the Medical Ethics Committee of the University Medical Centre Utrecht. Since 2011 he is Chairman of Neurology at the University Medical Center Utrecht. Since 2015 he is also director Research & Education of the Brain division of the UMCU. His research focuses on subarachnoid haemorrhage and intracranial aneurysms. He is (co-)author of more than 300 papers on subarachnoid haemorrhage and intracranial aneurysms in international peer reviewed journals and has given invited lectures at more than 25 universities in 4 continents, and at international conferences such as the World Congress of Neurology, the European Neurological Society, the World Stroke Congress, the International Stroke Congress, the European Stroke Congress and the World Federation of Interventional and Therapeutical Neuroradiology. In 2006 he gave the Stanley Davidson Lecture at the Neurology Symposium of the Royal College of Physicians of Edinburgh.

Research line and group

Research line
Stroke: subarachnoid haemorrhage and intracranial aneurysms
Number of PhD students
Number of postdocs

Personal fellowships and awards

  • 1998 European Stroke Research Award
  • 1999-2004 Clinical Established Investigator from the Netherlands Heart Foundation
  • 2006 Stanley Davidson Lecture

Most recent key publications

  • Dorhout Mees SM, Algra A, Vandertop WP, van Kooten F, Kuijsten HA, Boiten J, van Oostenbrugge RJ, Al-Shahi Salman R, Lavados PM, Rinkel GJ, van den Bergh WM; MASH-2 Study Group. Magnesium for aneurysmal subarachnoid haemorrhage (MASH-2): a randomised placebo-controlled trial. Lancet. 2012 Jul 7;380(9836):44-9.
  • Vlak MH, Algra A, Brandenburg R, Rinkel GJ. Prevalence of unruptured intracranial aneurysms, with emphasis on sex, age, comorbidity, country, and time period: a systematic review and meta-analysis. Lancet Neurol. 2011 Jul;10(7):626-36
  • Vlak MH, Rinkel GJ, Greebe P, van der Bom JG, Algra A. Trigger factors and their attributable risk for rupture of intracranial aneurysms: a case-crossover study. Stroke. 2011 Jul;42(7):1878-82
  • Rinkel GJ, Algra A. Long-term outcomes of patients with aneurysmal subarachnoid haemorrhage. Lancet Neurol. 2011 Apr;10(4):349-56
  • Bor AS, Koffijberg H, Wermer MJ, Rinkel GJ. Optimal screening strategy for familial intracranial aneurysms: a cost-effectiveness analysis. Neurology. 2010 May 25;74(21):1671-9