Corette Wierenga studied physics at the VU in Amsterdam (1996), followed by a PhD (2002) in neurobiology at the University of Amsterdam with Prof. Dr. Wytse Wadman. She worked as a postdoctoral researcher in the lab of Prof. Dr. Gina Turrigiano at Brandeis University (2002-2006), and at the Max Planck Institute of Neurobiology in the department of Prof. Dr. Tobias Bonhoeffer (2006-2011). In October 2011 she returned to the Netherlands and she is now an Assistant Professor at the Cell Biology Division at Utrecht University. In 2012 she received a ZonMW-VIDI grant.
My research focuses on understanding how new connections between nerve cells are formed and how these connections can be changed in the developing and adult brain. In particular, we study the activity-dependent formation and plasticity of inhibitory synapses in dendrites, with a special interest in interactions with nearby excitatory synapses. This research is aimed to solve outstanding fundamental questions in neuroscience as well as to provide important new insight in neurodevelopmental disorders.
We are using a combination of two-photon microscopy, electrophysiology, molecular and optical tools to study underlying molecular mechanisms.